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Epidermoid cyst in pineal region: A case report
J Korean Skull Base Soc 2024;19(1):74-78
Published online May 30, 2024
© 2024 Korean Skull Base Society.

Tae Seoung Kim, Hyun Jun Jo, Won Ki Yoon, Jong Hyun Kim, Taek Hyun Kwon, Joonho Byun

Department of Neurosurgery, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea
Correspondence to: Joonho Byun
Received July 27, 2023; Revised January 4, 2024; Accepted January 5, 2024.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ( which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
We are reporting a case involving a 25-year-old male patient who presented with mild headaches. A hyperdense mass in the pineal region was observed during a computed tomography scan. Subsequent magnetic resonance imaging revealed a heterogeneous mass in the pineal region, which did not exhibit contrast enhancement. The initial radiographic differential diagnoses included a germ cell tumor (teratoma) or an unusual fat-containing tumor, such as a lipoma. However, the patient’s tumor marker levels, including alpha-fetoprotein and beta-human chorionic gonadotropin, were within normal ranges. The patient underwent surgical resection, during which intraoperative findings indicated a relatively firm, whitish tumor. The mass was grossly total removed, and the patient recovered well without experiencing any neurological deficits. Histopathological examination of the excised tissue revealed a cyst lined by squamous epithelium, including keratin pearls, consistent with an epidermoid cyst. This case report highlights an unusual epidermoid cyst located in the pineal gland region, characterized by atypical radiological findings that posed challenges in achieving an accurate preoperative diagnosis.
Keywords : Epidermoid cyst, Pineal gland, Germ cell tumor

May 2024, 19 (1)
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